N-(4-((7R,14R)-1-(difluoromethoxy)-6-methyl-5-oxo-5,6,7,14-tetrahydro-7,14-methanobenzo[f]benzo[4,5]imidazo[1,2-a][1,4]diazocin-11-yl)phenyl)-P,P-dimethylphosphinic amide

(1S,3s)-3-(5-((7R,14R)-1-(difluoromethoxy)-6-(((1r,3R)-3-fluorocyclobutyl)methyl)-5-oxo-5,6,7,14-tetrahydro-7,14-methanobenzo[f]benzo[4,5]imidazo[1,2-a][1,4]diazocin-11-yl)pyrimidin-2-yl)-3-hydroxy-1-methylcyclobutanecarbonitrile

(7R,14R)-1-(difluoromethoxy)-11-(2-((1s,3S)-3-(fluoromethyl)-1-hydroxy-3-methylcyclobutyl)pyrimidin-5-yl)-6-((1-(fluoromethyl)cyclopropyl)methyl)-6,7-dihydro-7,14-methanobenzo[f]benzo[4,5]imidazo[1,2-a][1,4]diazocin-5(14H)-one

(7R,14R)-11-[(7S)-7-amino-6,7-dihydro-7-(hydroxymethyl)-5H-cyclopenta[b]pyridin-3-yl]-1-(difluoromethoxy)-6,7-dihydro-6-methyl-7,14-Methanobenzimidazo[1,2-b][2,5]benzodiazocin-5(14H)--one

(7R,14R)-11-[(7S)-7-amino-6,7-dihydro-7-methyl-5H-cyclopenta[b]pyridin-3-yl]-1-(difluoromethoxy)-6,7-dihydro-6-methyl-7,14-Methanobenzimidazo[1,2-b][2,5]benzodiazocin-5(14H)--one

(7R,14R)-11-(2-((R,Z)-1-amino-2-(fluoromethylene)cyclopentyl)pyrimidin-5-yl)-1-(difluoromethoxy)-6-methyl-6,7-dihydro-7,14-methanobenzo[f]benzo[4,5]imidazo[1,2-a][1,4]diazocin-5(14H)-one

(7R,14R)-11-(2-((1R,2R)-1-amino-2-(fluoromethyl)cyclopropyl)pyrimidin-5-yl)-1-(difluoromethoxy)-6-methyl-6,7-dihydro-7,14-methanobenzo[f]benzo[4,5]imidazo[1,2-a][1,4]diazocin-5(14H)-one

(7R,14R)-11-(2-((1r,3R)-1-amino-3-(fluoromethyl)cyclobutyl)pyrimidin-5-yl)-1-(difluoromethoxy)-6-methyl-6,7-dihydro-7,14-methanobenzo[f]benzo[4,5]imidazo[1,2-a][1,4]diazocin-5(14H)-one

(7R,14R)-11-[(3E,4R)-4-amino-3-(fluoromethylene)-3,4-dihydro-2H-pyrano[3,2-b]pyridin-7-yl]-1-(difluoromethoxy)-6,7-dihydro-6-methyl-7,14-Methanobenzimidazo[1,2-b][2,5]benzodiazocin-5(14H)--one

(7R,14R)-11-[(3S)-3-amino-2,3-dihydro-1-methyl-1H-pyrrolo[3,2-b]pyridin-6-yl]-1-(difluoromethoxy)-6,7-dihydro-6-methyl-7,14-Methanobenzimidazo[1,2-b][2,5]benzodiazocin-5(14H)--one

(7R,14R)-11-[(3S)-3-amino-2,3-dihydro-3-(1-propyn-1-yl)-furo[3,2-b]pyridin-6-yl]-1-(cyclopropylmethoxy)-6,7-dihydro-6-methyl-7,14-Methanobenzimidazo[1,2-b][2,5]benzodiazocin-5(14H)--one

(7R,14R)-11-[(4R)-4-amino-2,2-difluoro-3,4-dihydro-4-methyl-2H-pyrano[3,2-b]pyridin-7-yl]-1-(difluoromethoxy)-6,7-dihydro-6-methyl-7,14-Methanobenzimidazo[1,2-b][2,5]benzodiazocin-5(14H)--one

(7R,14R)-11-[(3S)-3-amino-3-ethyl-2,3-dihydrofuro[3,2-b]pyridin-6-yl]-1-(difluoromethoxy)-6,7-dihydro-6-methyl-7,14-Methanobenzimidazo[1,2-b][2,5]benzodiazocin-5(14H)--one

(7R,14R)-1-(difluoromethoxy)-6,7-dihydro-6-methyl-11-[6-[(1-oxido-2-phospholanyl)(1-oxido-5-phospholanyl)phosphinyl]pyridin-3-yl]-7,14-Methanobenzimidazo[1,2-b][2,5]benzodiazocin-5(14H)--one

(7R,14R)-11-(3-amino-3-cyclopropyl-2,2-difluoro-2,3-dihydrofuro[3,2-b]pyridin-6-yl)-1-(difluoromethoxy)-6,7-dihydro-6-methyl-7,14-Methanobenzimidazo[1,2-b][2,5]benzodiazocin-5(14H)--one

(7R,14R)-11-(4-amino-3,4-dihydro-2,2-dimethyl-2H-pyrano[3,2-b]pyridin-7-yl)-1-(difluoromethoxy)-6,7-dihydro-6-methyl-7,14-Methanobenzimidazo[1,2-b][2,5]benzodiazocin-5(14H)--one

(7R,14R)-11-(3-amino-3-ethyl-2,3-dihydrofuro[3,2-b]pyridin-6-yl)-1-(difluoromethoxy)-6,7-dihydro-6-methyl-7,14-Methanobenzimidazo[1,2-b][2,5]benzodiazocin-5(14H)--one

(7R,14R)-11-(4-amino-3,4-dihydro-2H-pyrano[3,2-b]pyridin-7-yl)-1-(cyclopropylmethoxy)-6,7-dihydro-6-methyl-7,14-Methanobenzimidazo[1,2-b][2,5]benzodiazocin-5(14H)--one

(7R,14R)-11-[(2S,4S)-4-amino-3,4-dihydro-2-methyl-2H-pyrano[3,2-b]pyridin-7-yl]-1-(difluoromethoxy)-6,7-dihydro-6-methyl-7,14-Methanobenzimidazo[1,2-b][2,5]benzodiazocin-5(14H)--one

(7R,14R)-11-[(1S)-1-amino-7-fluoro-2,3-dihydro-1H-inden-5-yl]-1-(difluoromethoxy)-6,7-dihydro-6-methyl-7,14-Methanobenzimidazo[1,2-b][2,5]benzodiazocin-5(14H)--one